Compound Q&A

How is (s)-Di-(3s,5s,7s)-adamantan-1-yl(benzyl)phosphine (CAS: 395116-70-8) typically synthesized?

Answer

(s)-Di-(3s,5s,7s)-adamantan-1-yl(benzyl)phosphine
The compound (s)-Di-(3s,5s,7s)-adamantan-1-yl(benzyl)phosphine is synthesized through a multi-step process involving the condensation of phosphorus trichloride with the corresponding 3,5,7-trisubstituted adamantane and benzyl alcohol. The reactions are typically carried out under an inert atmosphere to prevent decomposition. The yield and selectivity can be enhanced using catalytic amounts of Lewis acids or bases.

About

English Name (s)-Di-(3s,5s,7s)-adamantan-1-yl(benzyl)phosphine
Molecular Formula C27H37P
Molecular Weight 392.57 g/mol
SMILES C1C2CC3CC1CC(C2)(C3)P(CC4=CC=CC=C4)C56CC7CC(C5)CC(C7)C6
InChIKey ANIAFEJRWQDKDV-ANIFQACUSA-N
Last Updated: 2025-10-07 19:42

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