Compound Q&A

How is (2R)-2-Amino-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid (CAS: 64960-75-4) typically synthesized?

Answer

(2R)-2-Amino-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid
The synthesis of (2R)-2-Amino-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid (CAS: 64960-75-4) is typically achieved through a multi-step process involving the condensation of 2-methyl-2-propanol with 2-amino-4-oxobutanoic acid. Common catalysts include phosphorus oxychloride or a combination of thionyl chloride and pyridine. The overall yield can be improved by optimizing reaction conditions and using high purity starting materials.

About

CAS No 64960-75-4
English Name (2R)-2-Amino-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid
Molecular Formula C8H15NO4
Molecular Weight 189.21 g/mol
SMILES CC(C)(C)OC(=O)CC(C(=O)O)N
InChIKey MXWMFBYWXMXRPD-RXMQYKEDSA-N
Last Updated: 2025-10-05 08:54

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