Compound Q&A

How is 1-(2,3-Dichlorophenyl)piperazine (CAS: 41202-77-1) typically synthesized?

Answer

1-(2,3-Dichlorophenyl)piperazine
1-(2,3-Dichlorophenyl)piperazine can be synthesized using amination of 2,3-dichlorophenyl isocyanate with piperazine. The synthesis involves the use of a mild base like triethylamine and is conducted in anhydrous conditions. The reaction yields 85-90% of the product with good selectivity.

About

CAS No 41202-77-1
English Name 1-(2,3-Dichlorophenyl)piperazine
Molecular Formula C10H12Cl2N2
Molecular Weight 231.13 g/mol
SMILES C1CN(CCN1)C2=C(C(=CC=C2)Cl)Cl
InChIKey UDQMXYJSNNCRAS-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54

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