Compound Q&A
How is (R)-Salbutamol HCl (CAS: 50293-90-8) typically synthesized?
Answer
(R)-Salbutamol HCl (CAS: 50293-90-8) is typically synthesized via asymmetric synthesis using a chiral auxiliary, such as (-)-menthol. The process involves a catalytic hydrogenation of a key intermediate, followed by hydrochloric acid addition to form the final product. The yield is usually around 70-80%, and the reaction is carried out under mild conditions to maintain the chirality.
About
CAS No
50293-90-8
English Name
(R)-Salbutamol HCl ((R)-Albuterol HCl)
Molecular Formula
C13H22ClNO3
Molecular Weight
275.78 g/mol
SMILES
CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.Cl
InChIKey
OWNWYCOLFIFTLK-YDALLXLXSA-N
Last Updated: 2025-10-05 08:54
