(R)-Salbutamol HCl ((R)-Albuterol HCl)(CAS: 50293-90-8)

(R)-Salbutamol HCl (CAS: 50293-90-8) is a white crystalline powder with a molecular weight of approximately 251.71 g/mol. It is sparingly soluble in water and ethanol but soluble in organic solvents like methanol and dimethyl sulfoxide. Chemically, it is stable under normal conditions but can react with strong acids and bases. It is used as a bronchodilator in respiratory diseases.

(R)-Salbutamol HCl (CAS: 50293-90-8) is typically synthesized via asymmetric synthesis using a chiral auxiliary, such as (-)-menthol. The process involves a catalytic hydrogenation of a key intermediate, followed by hydrochloric acid addition to form the final product. The yield is usually around 70-80%, and the reaction is carried out under mild conditions to maintain the chirality.

(R)-Salbutamol HCl (CAS: 50293-90-8) is primarily used in the pharmaceutical industry to treat respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It is also used in polymer science for the synthesis of certain polymers and in the production of medical devices.

When handling (R)-Salbutamol HCl (CAS: 50293-90-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and eye protection. It should be stored under cool, dry conditions away from direct sunlight. In case of spill, it should be cleaned up immediately using appropriate absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.