Compound Q&A
How is 1-Bromo-2-(difluoromethoxy)benzene (CAS: 175278-33-8) typically synthesized?
Answer
1-Bromo-2-(difluoromethoxy)benzene (CAS: 175278-33-8) is typically synthesized via bromination of 2-(difluoromethoxy)benzene using bromine in the presence of a Lewis acid catalyst, such as aluminum bromide. The reaction is carried out in an inert solvent, usually dichloromethane. The yield is good, and the product can be isolated by recrystallization. This method provides a selective and efficient route to the compound.
About
CAS No
175278-33-8
English Name
1-Bromo-2-(difluoromethoxy)benzene
Molecular Formula
C7H5BrF2O
Molecular Weight
223.02 g/mol
SMILES
C1=CC=C(C(=C1)OC(F)F)Br
InChIKey
VHEICCMNYWNFQX-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42
