Compound Q&A

How is Ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate (CAS: 72490-01-8) typically synthesized?

Answer

Ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate
Ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate (CAS: 72490-01-8) is typically synthesized through a multi-step process involving the formation of a phenoxy intermediate, followed by its coupling with ethyl isocyanate. The synthesis employs mild conditions, using catalytic amounts of a Lewis acid as a catalyst. The overall yield is good, with high regioselectivity and good purity of the final product.

About

CAS No 72490-01-8
English Name Ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate
Molecular Formula C17H19NO4
Molecular Weight 301.34 g/mol
SMILES CCOC(=O)NCCOc1ccc(cc1)Oc2ccccc2
InChIKey HJUFTIJOISQSKQ-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51

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