Compound Q&A
How is (17beta)-3-Oxoandrost-4-ene-17-carboxylic acid (CAS: 302-97-6) typically synthesized?
Answer
(17beta)-3-Oxoandrost-4-ene-17-carboxylic acid can be synthesized through the reduction of androst-4-ene-17-one followed by carboxylation. Commonly, this involves the use of lithium aluminum hydride (LAH) for reduction and then the addition of carbon dioxide in the presence of a base to introduce the carboxylic acid functionality. The reaction is typically carried out under anhydrous conditions to prevent side reactions.
About
CAS No
302-97-6
English Name
(17beta)-3-Oxoandrost-4-ene-17-carboxylic acid
Molecular Formula
C20H28O3
Molecular Weight
316.44 g/mol
SMILES
CC12CCC3C(C1CCC2C(=O)O)CCC4=CC(=O)CCC34C
InChIKey
YQACAXHKQZCEOI-UDCWSGSHSA-N
Last Updated: 2025-10-01 13:51
