Compound Q&A
How is 1-Fluoro-4-nitro-2-(trifluoromethyl)benzene (CAS: 400-74-8) typically synthesized?
Answer
1-Fluoro-4-nitro-2-(trifluoromethyl)benzene is typically synthesized by the nitration of 1-fluoro-2-(trifluoromethyl)benzene using a mixture of nitric and sulfuric acids. The reaction is carried out in a solvent like acetic acid at a temperature around 50°C. The product is then purified by recrystallization from a suitable solvent to obtain the crystalline form.
About
CAS No
400-74-8
English Name
1-Fluoro-4-nitro-2-(trifluoromethyl)benzene
Molecular Formula
C7H3F4NO2
Molecular Weight
209.1 g/mol
SMILES
C1=CC(=C(C=C1[N+](=O)[O-])C(F)(F)F)F
InChIKey
DNTHMWUMRGOJRY-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
