Compound Q&A

How is (2S)-2-Amino-3-methyl-1-pentanol (CAS: 24629-25-2) typically synthesized?

Answer

(2S)-2-Amino-3-methyl-1-pentanol
(2S)-2-Amino-3-methyl-1-pentanol is synthesized via a multi-step process starting from 3-methyl-1-pentanol. The key reaction involves the nucleophilic addition of ammonia to 3-methyl-1-pentanal followed by reduction. A catalyst like palladium on carbon is often used for the reduction step to achieve high yield and selectivity. This method ensures the formation of the correct (2S) stereochemistry, making it suitable for pharmaceutical applications.

About

CAS No 24629-25-2
English Name (2S)-2-Amino-3-methyl-1-pentanol
Molecular Formula C6H15NO
Molecular Weight 117.19 g/mol
SMILES CCC(C)C(CO)N
InChIKey VTQHAQXFSHDMHT-PRJDIBJQSA-N
Last Updated: 2025-10-01 13:51

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