Compound Q&A

How is 5-Aminonicotinic acid (CAS: 24242-19-1) typically synthesized?

Answer

5-Aminonicotinic acid
5-Aminonicotinic acid can be synthesized through the reduction of nicotinic acid with sodium borohydride in a polar aprotic solvent like dimethyl sulfoxide (DMSO). The reaction is catalyzed by sodium borohydride, and the yield can reach up to 85%. Other methods include the use of hydrogenation in the presence of palladium catalysts.

About

CAS No 24242-19-1
English Name 5-Aminonicotinic acid
Molecular Formula C6H6N2O2
Molecular Weight 138.13 g/mol
EINECS 625-282-8
SMILES C1=C(C=NC=C1N)C(=O)O
InChIKey BYIORJAACCWFPU-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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