Compound Q&A

What are the main uses of YM155 (CAS: 781661-94-7)?

Answer

YM155 (Sepantronium Bromide)
YM155 is primarily used in pharmaceutical research as an inhibitor of the nuclear export protein XPO1. It is used to study the effects of perturbing nuclear transport in cells, which can help in understanding and developing treatments for diseases including cancers. Its use is mainly confined to laboratory research and not for clinical applications.

About

English Name YM155 (Sepantronium Bromide)
Molecular Formula C20H19BrN4O3
Molecular Weight 443.29 g/mol
SMILES CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
InChIKey QBIYUDDJPRGKNJ-UHFFFAOYSA-M
Last Updated: 2025-09-28 00:26

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