Compound Q&A
How is (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid (CAS: 125238-99-5) typically synthesized?
Answer
![(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid](https://static.chemtradehub.com/structs/125/125238-99-5-c6e4.webp "(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid")
The compound can be synthesized through multistep reactions involving coupling of fluorenylmethoxycarbonyl protected amino acids with 2-methyl-2-propanol via a carbonyl compound. Common methods include peptide coupling reactions using standard Fmoc chemistry and subsequent deprotection steps. Reaction conditions typically involve the use of appropriate bases and solvents to ensure high yields and selectivity.
About
CAS No
125238-99-5
English Name
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid
Molecular Formula
C24H28N2O6
Molecular Weight
440.5 g/mol
SMILES
CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)O
InChIKey
LIWKOFAHRLBNMG-FQEVSTJZSA-N
Last Updated: 2025-09-26 00:09
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