Compound Q&A
How is 4-Amino-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylic acid (CAS: 123654-26-2) typically synthesized?
Answer
4-Amino-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylic acid is typically synthesized via a multi-step process. Common methods involve the initial synthesis of 5-chloro-2,3-dihydro-1-benzofuran followed by the introduction of the amine group. This can be achieved through aminomethylation or direct amination. The overall yield is around 75-85%, and the process requires careful control of reaction conditions to achieve high selectivity and purity.
About
CAS No
123654-26-2
English Name
4-Amino-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylic acid
Molecular Formula
C9H8ClNO3
Molecular Weight
213.62 g/mol
SMILES
C1COC2=C1C(=C(C=C2C(=O)O)Cl)N
InChIKey
KRMUVKSAOVLXLF-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
