Compound Q&A

How is Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate (CAS: 35677-89-5) typically synthesized?

Answer

Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate
Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate can be synthesized via the reaction of benzyl chloroformate with (3S)-2-oxotetrahydrofuran in the presence of a base such as diisopropylethylamine. The reaction is carried out at room temperature, yielding the product in good to excellent yield with high selectivity.

About

CAS No 35677-89-5
English Name Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate
Molecular Formula C12H13NO4
Molecular Weight 235.24 g/mol
SMILES C1COC(=O)C1NC(=O)OCC2=CC=CC=C2
InChIKey FKWDZIFOVOUDAG-JTQLQIEISA-N
Last Updated: 2025-09-25 13:48

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