Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate(CAS: 35677-89-5)

Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate is a white crystalline solid with a molecular weight of approximately 240.26 g/mol. It is slightly soluble in water and more soluble in organic solvents such as methanol and ethanol. The compound is known for its moderate reactivity, particularly in amide bond formation and nucleophilic substitution reactions.

Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate can be synthesized via the reaction of benzyl chloroformate with (3S)-2-oxotetrahydrofuran in the presence of a base such as diisopropylethylamine. The reaction is carried out at room temperature, yielding the product in good to excellent yield with high selectivity.

Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate is mainly used in the pharmaceutical industry for the synthesis of various drug molecules. It is also utilized in the polymer industry for modifying polymer properties and in the production of sensors and semiconductors due to its unique chemical structure.

Proper handling of Benzyl [(3S)-2-oxotetrahydro-3-furanyl]carbamate includes the use of personal protective equipment such as gloves, goggles, and lab coat. Handling should be done in a well-ventilated area or a fume hood. Spills should be carefully cleaned up with appropriate absorbent materials. The material safety data sheet (MSDS) should be consulted for detailed handling and emergency procedures.