Compound Q&A

How is (4-(tert-Butoxycarbonyl)phenyl)boronic acid (CAS: 850568-54-6) typically synthesized?

Answer

(4-(tert-Butoxycarbonyl)phenyl)boronic acid
(4-(tert-Butoxycarbonyl)phenyl)boronic acid is usually synthesized from tert-butoxycarbonyl phenyl boronic acid via a boronic acid protection step using tert-butoxycarbonyl chloride. The reaction is typically performed at room temperature in the presence of a base like triethylamine in a solvent such as dichloromethane or tetrahydrofuran. The purity and yield can be optimized by adjusting the reaction conditions and using appropriate purification techniques.

About

English Name (4-(tert-Butoxycarbonyl)phenyl)boronic acid
Molecular Formula C11H15BO4
Molecular Weight 222.049 g/mol
SMILES B(C1=CC=C(C=C1)C(=O)OC(C)(C)C)(O)O
InChIKey QMVMDYSTJSUDKC-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48

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