Compound Q&A

How is N-(2-hydroxyethyl)acetamide (CAS: 142-26-7) typically synthesized?

Answer

N-(2-hydroxyethyl)acetamide
N-(2-hydroxyethyl)acetamide is typically synthesized via the reaction of acetic anhydride with ethylene glycol. The process involves the condensation of the carboxylic acid group of acetic anhydride with the hydroxyl group of ethylene glycol in the presence of an acid catalyst such as sulfuric acid. The product is then purified by recrystallization from water or methanol.

About

CAS No 142-26-7
English Name N-(2-hydroxyethyl)acetamide
Molecular Formula C4H9NO2
Molecular Weight 103.12 g/mol
SMILES CC(=O)NCCO
InChIKey PVCJKHHOXFKFRP-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23

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