Compound Q&A
How is 2-Chloro-N-methoxy-N-methylacetamide (CAS: 67442-07-3) typically synthesized?
Answer
2-Chloro-N-methoxy-N-methylacetamide is typically synthesized via nucleophilic substitution reactions. The reaction involves the chlorination of methyl acetamide in the presence of methanol and a phase-transfer catalyst like tetra-n-butylammonium chloride. The synthetic route provides good selectivity and yields up to 85%.
About
CAS No
67442-07-3
English Name
2-Chloro-N-methoxy-N-methylacetamide
Molecular Formula
C4H8ClNO2
Molecular Weight
137.57 g/mol
SMILES
CN(C(=O)CCl)OC
InChIKey
SCOJKGRNQDKFRP-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
