Compound Q&A
How is Candesartan Cilexetil Impurity 9 (CAS: 136285-67-1) typically synthesized?
Answer
Candesartan Cilexetil Impurity 9 (CAS: 136285-67-1) is synthesized via a multistep process involving acylation, cyclization, and esterification reactions. Common catalysts used include sulfonyl chlorides and carboxylic acids. The synthesis typically achieves a yield of around 75%, with high selectivity towards the desired impurity. Detailed synthetic routes and purification methods can be found in chemical literature.
About
CAS No
136285-67-1
English Name
Candesartan Cilexetil Impurity 9
Molecular Formula
C23H19N3O4
Molecular Weight
401.4 g/mol
SMILES
CCOC(=O)C1=C(C(=CC=C1)[N+](=O)[O-])NCC2=CC=C(C=C2)C3=CC=CC=C3C#N
InChIKey
CHPMKOFPDCKNBG-UHFFFAOYSA-N
Last Updated: 2025-09-23 10:23
