Compound Q&A

How is (2S)-Amino(4-fluorophenyl)acetic acid (CAS: 19883-57-9) typically synthesized?

Answer

(2S)-Amino(4-fluorophenyl)acetic acid
(2S)-Amino(4-fluorophenyl)acetic acid (CAS: 19883-57-9) is typically synthesized via a multistep process involving the formation of a protected 4-fluorophenol derivative, followed by its coupling with an acetylating agent, and finally, the deprotection step. This process can yield up to 80% isolated yield with high selectivity for the (2S) stereochemistry.

About

CAS No 19883-57-9
English Name (2S)-Amino(4-fluorophenyl)acetic acid
Molecular Formula C8H8FNO2
Molecular Weight 169.15 g/mol
SMILES C1=CC(=CC=C1C(C(=O)O)N)F
InChIKey JKFYKCYQEWQPTM-ZETCQYMHSA-N
Last Updated: 2025-09-22 19:21

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