(2S)-Amino(4-fluorophenyl)acetic acid(CAS: 19883-57-9)

(2S)-Amino(4-fluorophenyl)acetic acid (CAS: 19883-57-9) is a crystalline solid with a molecular weight of approximately 191.16 g/mol. It has a solubility of about 1.5 g/L in water at 25°C. Chemically, it is moderately reactive, exhibiting susceptibility to hydrolysis under basic conditions. It is sparingly soluble in common organic solvents like ethanol and methanol.

(2S)-Amino(4-fluorophenyl)acetic acid (CAS: 19883-57-9) is typically synthesized via a multistep process involving the formation of a protected 4-fluorophenol derivative, followed by its coupling with an acetylating agent, and finally, the deprotection step. This process can yield up to 80% isolated yield with high selectivity for the (2S) stereochemistry.

(2S)-Amino(4-fluorophenyl)acetic acid (CAS: 19883-57-9) is primarily used in the pharmaceutical industry due to its structural similarity to certain amino acids, making it a valuable intermediate for drug synthesis. It is also explored in the polymer industry for its potential as a monomer and in the semiconductor industry for its use in photoresists.

When handling (2S)-Amino(4-fluorophenyl)acetic acid (CAS: 19883-57-9), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and other sources of heat. In case of a spill, it should be cleaned up using appropriate absorbent materials and flushed with water. For detailed safety information, refer to the Safety Data Sheet (SDS).