Compound Q&A

How is Methyl 2-amino-4,5-dimethoxybenzoate (CAS: 26759-46-6) typically synthesized?

Answer

Methyl 2-amino-4,5-dimethoxybenzoate
Methyl 2-amino-4,5-dimethoxybenzoate (CAS: 26759-46-6) is typically synthesized by the reaction of 4,5-dimethoxybenzoic acid with methylamine hydrochloride. The reaction is performed in the presence of a base such as potassium carbonate, and the product is isolated and purified by recrystallization. The yield is usually around 75-85%, and the reaction is highly selective.

About

CAS No 26759-46-6
English Name Methyl 2-amino-4,5-dimethoxybenzoate
Molecular Formula C10H13NO4
Molecular Weight 211.22 g/mol
SMILES COC1=C(C=C(C(=C1)C(=O)OC)N)OC
InChIKey QQFHCCQSCQBKBG-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21

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