Compound Q&A

Are there alternatives to (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid (CAS: 3398-22-9) in synthesis?

Answer

(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
In the synthesis of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid (CAS: 3398-22-9), several alternatives can be used. For instance, (2R,4R)- and (2S,4S)-isomers can serve as viable alternatives. Common alternative reagents include amino acids like proline, which can be modified to achieve similar structural properties. Utilizing these alternatives can help in achieving the desired product with better efficiency and safety.

About

CAS No 3398-22-9
English Name (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
Molecular Formula C5H9NO3
Molecular Weight 131.13 g/mol
SMILES C1C(CNC1C(=O)O)O
InChIKey PMMYEEVYMWASQN-IUYQGCFVSA-N
Last Updated: 2025-09-21 10:38

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