Compound Q&A
How is Ethyl 5-amino-1-benzofuran-2-carboxylate (CAS: 174775-48-5) typically synthesized?
Answer
Ethyl 5-amino-1-benzofuran-2-carboxylate (CAS: 174775-48-5) can be synthesized via a multi-step process starting with ethyl benzoate and aniline. The key steps involve condensation followed by alkylation, then reduction, and finally the formation of the amino group. Commonly used catalysts include various Lewis acids and transition metal complexes. The overall yield is around 70-80%, and the method is selective and efficient.
About
CAS No
174775-48-5
English Name
Ethyl 5-amino-1-benzofuran-2-carboxylate
Molecular Formula
C11H11NO3
Molecular Weight
205.21 g/mol
SMILES
CCOC(=O)C1=CC2=C(O1)C=CC(=C2)N
InChIKey
YFFLLDHEEWSHQG-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14
