Compound Q&A
How is 2-(Trifluoromethyl)nicotinic acid (CAS: 131747-43-8) typically synthesized?
Answer
2-(Trifluoromethyl)nicotinic acid can be synthesized through the trifluoromethylation of nicotinic acid using reagents such as triflic anhydride. Common methods include nucleophilic substitution reactions in the presence of appropriate bases. The synthesis typically yields a high percentage of the desired product with good selectivity.
About
CAS No
131747-43-8
English Name
2-(Trifluoromethyl)nicotinic acid
Molecular Formula
C7H4F3NO2
Molecular Weight
191.11 g/mol
SMILES
C1=CC(=C(N=C1)C(F)(F)F)C(=O)O
InChIKey
BFROETNLEIAWNO-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49
