Compound Q&A

How is Flurbiprofen Axetil (CAS: 91503-79-6) typically synthesized?

Answer

Flurbiprofen Axetil
Flurbiprofen Axetil is typically synthesized through a esterification reaction between flurbiprofen and acetic anhydride, followed by acetylation. Common catalysts include acid catalysts like sulfuric acid. The reaction is carried out under mild conditions to achieve high selectivity and yield, with purification steps involving recrystallization and vacuum drying.

About

CAS No 91503-79-6
English Name Flurbiprofen Axetil
Molecular Formula C19H19FO4
Molecular Weight 330.36 g/mol
SMILES CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)OC(C)OC(=O)C
InChIKey ALIVXCSEERJYHU-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49

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