Compound Q&A
How is 4-Chloro-6-methoxy-2-pyrimidinamine (CAS: 5734-64-5) typically synthesized?
Answer
4-Chloro-6-methoxy-2-pyrimidinamine is typically synthesized via the reaction of 6-chloropyrimidine with methanol followed by treatment with sodium hydroxide. Commonly, this involves the condensation of 6-chloropyrimidine with methanol to form the 5-chloro-6-methoxypyrimidine, which is then reduced to the amine using a suitable reducing agent such as sodium borohydride.
About
CAS No
5734-64-5
English Name
4-Chloro-6-methoxy-2-pyrimidinamine
Molecular Formula
C5H6ClN3O
Molecular Weight
159.58 g/mol
SMILES
COC1=CC(=NC(=N1)N)Cl
InChIKey
VFEYBTFCBZMBAU-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49
