Compound Q&A
How is 1-Bromo-3-fluoro-2-nitrobenzene (CAS: 886762-70-5) typically synthesized?
Answer
1-Bromo-3-fluoro-2-nitrobenzene (CAS: 886762-70-5) is synthesized by bromination of 3-fluoro-2-nitrobenzene with bromine in the presence of a phase transfer catalyst, such as tetra-n-butylammonium bromide. The reaction is typically conducted in a non-aqueous solvent like acetonitrile or N,N-dimethylformamide (DMF). The yield is usually high, and the product is isolated by recrystallization or distillation.
About
CAS No
886762-70-5
English Name
1-Bromo-3-fluoro-2-nitrobenzene
Molecular Formula
C6H3BrFNO2
Molecular Weight
220 g/mol
SMILES
C1=CC(=C(C(=C1)Br)[N+](=O)[O-])F
InChIKey
VFPAOFBPEYCAAZ-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15
