Compound Q&A
How is 3-[(E)-2-(4-Hydroxyphenyl)vinyl]-5-methoxyphenol (CAS: 42438-89-1) typically synthesized?
Answer
![3-[(E)-2-(4-Hydroxyphenyl)vinyl]-5-methoxyphenol](https://static.chemtradehub.com/structs/424/42438-89-1-f7f1.webp "3-[(E)-2-(4-Hydroxyphenyl)vinyl]-5-methoxyphenol")
3-[(E)-2-(4-Hydroxyphenyl)vinyl]-5-methoxyphenol (CAS: 42438-89-1) is typically synthesized through a series of reactions involving coupling of a vinyl bromide with a 4-hydroxybenzophenone derivative followed by methylation. This process often requires the use of Lewis acids and mild heating to promote the coupling reaction. The overall yield is around 70%, with high selectivity for the desired product.
About
CAS No
42438-89-1
English Name
3-[(E)-2-(4-Hydroxyphenyl)vinyl]-5-methoxyphenol
Molecular Formula
C15H14O3
Molecular Weight
242.27 g/mol
SMILES
COc1cc(cc(c1)O)/C=C/c2ccc(cc2)O
InChIKey
KUWZXOMQXYWKBS-NSCUHMNNSA-N
Last Updated: 2025-09-09 19:18
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