Compound Q&A

How is Alvocidib (CAS: 146426-40-6) typically synthesized?

Answer

Alvocidib (Flavopiridol)
Alvocidib (CAS: 146426-40-6) is synthesized through a multi-step process involving condensation, reduction, and acylation reactions. The synthesis often uses catalytic amounts of palladium and other transition metals, with yields typically ranging from 50-70%.

About

English Name Alvocidib (Flavopiridol)
Molecular Formula C21H20ClNO5
Molecular Weight 401.85 g/mol
SMILES CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O
InChIKey BIIVYFLTOXDAOV-YVEFUNNKSA-N
Last Updated: 2025-09-09 19:18

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