Compound Q&A
How is 2,6-Dichloro-5-fluoronicotinamide (CAS: 113237-20-0) typically synthesized?
Answer
2,6-Dichloro-5-fluoronicotinamide can be synthesized via a multi-step process involving the reaction of 3-chloro-5-fluoronicotinonitrile with hydrochloric acid. Common catalysts include phosphorus pentoxide or pyridine. The yield is typically around 70-80%, and the reaction is selective towards the desired product.
About
CAS No
113237-20-0
English Name
2,6-Dichloro-5-fluoronicotinamide
Molecular Formula
C6H3Cl2FN2O
Molecular Weight
209.01 g/mol
SMILES
NC(=O)c1cc(F)c(nc1Cl)Cl
InChIKey
ZVYNUGSPFZCYEV-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
