Compound Q&A

How is Bexarotene (CAS: 153559-49-0) typically synthesized?

Answer

Bexarotene
Bexarotene is typically synthesized through a multistep process involving acylation of a primary alcohol followed by oxidation and reduction. Commonly used catalysts include molecular sieves and various transition metals. The overall yield is around 50%, with good selectivity towards the desired product.

About

English Name Bexarotene
Molecular Formula C24H28O2
Molecular Weight 348.49 g/mol
SMILES CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
InChIKey NAVMQTYZDKMPEU-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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