Compound Q&A
How is 2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid (CAS: 117724-63-7) typically synthesized?
Answer
2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid is typically synthesized via the reaction of 2-methylthiazole-4-carboxylic acid with trifluoromethylsulfonyl chloride, followed by hydrolysis. This process involves the use of a phase transfer catalyst and is carried out under mild conditions to achieve good yield and selectivity.
About
CAS No
117724-63-7
English Name
2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid
Molecular Formula
C6H4F3NO2S
Molecular Weight
211.16 g/mol
SMILES
CC1=NC(=C(S1)C(=O)O)C(F)(F)F
InChIKey
REKJPVUFKQYMHW-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
