Compound Q&A

How is 3-Methoxy-N-phenylaniline (CAS: 101-16-6) typically synthesized?

Answer

3-Methoxy-N-phenylaniline
3-Methoxy-N-phenylaniline (CAS: 101-16-6) is typically synthesized via a condensation reaction between aniline and methanol in the presence of an acid catalyst like sulfuric acid. The reaction is performed at elevated temperatures, often above 100°C, and the yield is generally around 85-90%. The product is purified by recrystallization from ethanol or methanol.

About

CAS No 101-16-6
English Name 3-Methoxy-N-phenylaniline
Molecular Formula C13H13NO
Molecular Weight 199.25 g/mol
SMILES COC1=CC=CC(=C1)NC2=CC=CC=C2
InChIKey MKASXAGBWHIGCF-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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