Compound Q&A
How is (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol (CAS: 643-12-9) typically synthesized?
Answer
(1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol can be synthesized via a stereoselective hydrogenation of a suitable isomer of cyclohexanone oxime. Commonly, this process involves the use of a chiral catalyst to achieve high enantioselectivity. The yield is generally around 70-80%, and the purity can be improved through recrystallization.
About
CAS No
643-12-9
English Name
(1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol
Molecular Formula
C6H12O6
Molecular Weight
180.16 g/mol
SMILES
[C@@H]1([C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)O)O)O)O)O
InChIKey
CDAISMWEOUEBRE-LKPKBOIGSA-N
Last Updated: 2025-09-08 00:42
