Compound Q&A
How is Acalabrutinib (CAS: 1420477-60-6) typically synthesized?
Answer
Acalabrutinib (CAS: 1420477-60-6) is synthesized through a multi-step process involving the modification of a defined starting material. The synthesis typically involves a series of reactions including alkylation, amination, and acylation, with the use of specific catalysts and reagents. The final step involves purification and crystallization to obtain the desired product. The overall yield is around 50-60%, with high selectivity towards the target compound.
About
CAS No
1420477-60-6
English Name
Acalabrutinib
Molecular Formula
C26H23N7O2
Molecular Weight
30.07 g/mol
SMILES
CC#CC(=O)N1CCC[C@H]1c2nc(c3ccc(cc3)C(=O)Nc4ccccn4)c5c(N)nccn25
InChIKey
WDENQIQQYWYTPO-IBGZPJMESA-N
Last Updated: 2025-09-08 00:42
