Compound Q&A
How is (2S)-6-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid (CAS: 150629-67-7) typically synthesized?
Answer
![(2S)-6-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid](https://static.chemtradehub.com/structs/150/150629-67-7-a217.webp "(2S)-6-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid")
This compound is typically synthesized via a peptide coupling reaction using fluorenylmethyloxycarbonyl (Fmoc) chemistry. The synthesis involves protecting groups, coupling steps, and deprotection. Commonly, Fmoc-protected amino acids are used, and the reaction is carried out in an organic solvent such as DMF with a coupling reagent like HATU or DIC. Yields are usually around 70-80%, with high selectivity.
About
CAS No
150629-67-7
English Name
(2S)-6-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
Molecular Formula
C31H36N2O6
Molecular Weight
532.64 g/mol
SMILES
CC(=C1C(=O)CC(C)(C)CC1=O)NCCCC[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(=O)O
InChIKey
ZPSRBXWVBNVFTO-VWLOTQADSA-N
Last Updated: 2025-09-08 00:42
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