Compound Q&A
How is 1-Fluoro-3-nitrobenzene (CAS: 402-67-5) typically synthesized?
Answer
1-Fluoro-3-nitrobenzene is typically synthesized through the nitration of 1-fluorobenzene. This process involves treating 1-fluorobenzene with a mixture of concentrated sulfuric acid and concentrated nitric acid under controlled conditions. The reaction is exothermic, and proper cooling is necessary to prevent over-nitration. The product can be isolated by extraction and recrystallization.
About
CAS No
402-67-5
English Name
1-Fluoro-3-nitrobenzene
Molecular Formula
C6H4FNO2
Molecular Weight
141.1 g/mol
SMILES
C1=CC(=CC(=C1)F)[N+](=O)[O-]
InChIKey
WMASLRCNNKMRFP-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
