Compound Q&A
How is 5-Aminofluorescein (CAS: 3326-34-9) typically synthesized?
Answer
5-Aminofluorescein (CAS: 3326-34-9) is synthesized by the reaction of 3-hydroxy-5-nitrofluorescein with an amine. Commonly, this involves the reduction of the nitro group followed by an alkylation step to introduce the amine functionality. The reaction is typically carried out in the presence of a catalyst such as sodium hydride, and the yield is usually around 70-80%.
About
CAS No
3326-34-9
English Name
5-Aminofluorescein
Molecular Formula
C20H13NO5
Molecular Weight
347.33 g/mol
SMILES
Nc1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc53
InChIKey
GZAJOEGTZDUSKS-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19