Compound Q&A

How is 2-Chloronicotinaldehyde (CAS: 36404-88-3) typically synthesized?

Answer

2-Chloronicotinaldehyde
2-Chloronicotinaldehyde is typically synthesized through the condensation of 2-chloronicotinamide with formaldehyde. The reaction usually involves the use of a strong base like sodium hydroxide or potassium hydroxide to enhance the nucleophilicity of the amide group, leading to a high yield of the desired product.

About

CAS No 36404-88-3
English Name 2-Chloronicotinaldehyde
Molecular Formula C6H4ClNO
Molecular Weight 141.56 g/mol
SMILES C1=CC(=C(N=C1)Cl)C=O
InChIKey KHPAGGHFIDLUMB-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

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