Compound Q&A
How is 1-(2-Chlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanol hydrochloride (CAS: 56776-01-3) typically synthesized?
Answer
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1-(2-Chlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanol hydrochloride is typically synthesized by the reaction of 2-chloroaniline with 2-methyl-2-propanol followed by acetylation and hydrolysis. The reaction is performed in the presence of a suitable base and catalyst, and the product is isolated by recrystallization. The yield is around 75%, and the selectivity is good, with minimal side products.
About
CAS No
56776-01-3
English Name
1-(2-Chlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanol hydrochloride (1:1)
Molecular Formula
C12H19Cl2NO
Molecular Weight
264.19 g/mol
SMILES
CC(C)(C)NCC(C1=CC=CC=C1Cl)O.Cl
InChIKey
RSLNRVYIRDVHLY-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
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