Compound Q&A
How is tert-butyl 4-aminobenzoate (CAS: 18144-47-3) typically synthesized?
Answer
Tert-butyl 4-aminobenzoate is typically synthesized via the reaction of 4-bromobenzoic acid with tert-butylamine in the presence of a suitable base like sodium hydride. The product is isolated by recrystallization from an appropriate solvent. The reaction is highly selective and provides a yield of about 75-85%.
About
CAS No
18144-47-3
English Name
tert-butyl 4-aminobenzoate
Molecular Formula
C11H15NO2
Molecular Weight
193.25 g/mol
SMILES
CC(C)(C)OC(=O)C1=CC=C(C=C1)N
InChIKey
KYORUZMJUKHKFS-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
