(1R,3S,5R)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID(CAS: 197142-34-0)

This compound is a white or off-white crystalline solid with a molecular weight of approximately 246.36 g/mol. It has a pKa of around 4.0, indicating moderate acidity. The compound is soluble in common organic solvents like DMSO and methanol but is less soluble in water. It shows moderate reactivity towards bases and nucleophiles. It also exhibits good stability under normal conditions but may degrade under strongly acidic or basic conditions.

This compound can be synthesized via a multi-step process including the formation of a cyclic amide and subsequent protection of the amine. Commonly, a protected amine is reacted with an acyl chloride in the presence of a base to form the cyclic ester. The specific conditions, such as the choice of catalysts (e.g., DMAP, HOBt), solvents, and temperatures, can vary depending on the method used. The overall yield is typically around 70-80%.

This compound is primarily used in the pharmaceutical industry as a precursor to more complex molecules and in the development of certain drugs. It may also find applications in the production of certain polymers and as a sensing material due to its chemical reactivity. Its use in semiconductors and electronic materials is less common but is explored for specific applications.

When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a dry, cool place away from direct sunlight. Spills should be handled carefully; sweep up solid materials and dispose of them according to local regulations. If inhaled or ingested, seek medical attention immediately. Always refer to the Safety Data Sheet (SDS) for specific handling and emergency procedures.