Leucine-enkephalin, arg-arg-val-gly-arg-pro-glu-trp-trp-met-asp-tyr-gly-(CAS: 76622-26-9)

Leucine-enkephalin (CAS: 76622-26-9) is a peptide with a molecular weight of approximately 754.75 g/mol. It is a white to off-white crystalline powder with good solubility in water but has limited solubility in organic solvents. It is stable under normal conditions but can degrade under acidic or basic conditions. It is reactive towards proteases and has limited reactivity towards other common chemical reagents.

Leucine-enkephalin (CAS: 76622-26-9) is typically synthesized through solid-phase peptide synthesis (SPPS). The synthesis involves the stepwise addition of amino acids to a growing peptide chain on a solid support, with appropriate protecting groups. Commonly used coupling agents include DCC (dicyclohexylcarbodiimide) and HOBt (1-hydroxybenzotriazole). The yield is typically around 70-80%, with good selectivity towards the desired product.

Leucine-enkephalin (CAS: 76622-26-9) is primarily used in the pharmaceutical industry for research purposes, including drug discovery and development. It is also used in the biochemical and biotechnology sectors for various applications such as enzyme studies and peptide-based assays. Limited applications are found in the polymer and semiconductor industries due to its specific biological activity.

When handling Leucine-enkephalin (CAS: 76622-26-9), it is important to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. Store it in a cool, dry place away from direct sunlight. Use a fume hood for any handling that may generate vapors. In case of spills, neutralize with an appropriate reagent and dispose of according to local regulations. Always consult a Material Safety Data Sheet (MSDS) for specific handling instructions and emergency procedures.