2-[(2-Phenylethyl)sulfanyl]-1H-benzimidazole(CAS: 167483-31-0)

2-[(2-Phenylethyl)sulfanyl]-1H-benzimidazole is a white to off-white crystalline solid with a molecular weight of approximately 288.34 g/mol. Its solubility in water is low, with a solubility of about 0.1 g/L at 25°C. It is known for its stability under acidic and basic conditions, but it may react with strong oxidizing agents. It is also relatively unreactive towards nucleophiles.

2-[(2-Phenylethyl)sulfanyl]-1H-benzimidazole is typically synthesized through a multi-step process involving the reaction of 2-aminobenzimidazole with 2-phenylethyl mercaptan. The synthesis involves condensation, followed by sulfenylation. This method yields a product with high purity and selectivity. The overall yield can range from 70% to 85%.

2-[(2-Phenylethyl)sulfanyl]-1H-benzimidazole is used in various industries, primarily in pharmaceuticals, where it acts as an antiviral agent. It is also used in the development of new materials for sensors and semiconductors due to its unique electronic and optical properties. In polymer science, it can be used as a stabilizer or for functionalization of polymers.

When handling 2-[(2-Phenylethyl)sulfanyl]-1H-benzimidazole, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or under a fume hood. Spills should be cleaned up with caution, using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.