2-[4-(Benzyloxy)phenyl]ethanol(CAS: 61439-59-6)

2-[4-(Benzyloxy)phenyl]ethanol is a clear, colorless liquid with a molecular weight of approximately 252.29 g/mol. It has a pKa of around 10.5 and is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. This compound is known for its low reactivity under normal conditions, making it stable in air and common solvents.

2-[4-(Benzyloxy)phenyl]ethanol can be synthesized by reacting benzyl bromide with p-hydroxybenzaldehyde in the presence of sodium hydroxide. The reaction yields a mixture that can be purified by recrystallization. Alternatively, it can be prepared from 4-benzyloxybenzaldehyde through reduction with sodium borohydride, followed by hydrolysis.

2-[4-(Benzyloxy)phenyl]ethanol is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer or intermediate, and in the chemical sensor field for its ability to act as a chromogenic reagent.

When handling 2-[4-(Benzyloxy)phenyl]ethanol, appropriate personal protective equipment (PPE) should be worn, including gloves and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up carefully following standard procedures, and the area should be ventilated. For more detailed safety information, refer to the Safety Data Sheet (SDS).