5-Bromo-1-isoindolinone(CAS: 552330-86-6)

5-Bromo-1-isoindolinone (CAS: 552330-86-6) is a crystalline compound with a molecular weight of approximately 221.02 g/mol. It has a melting point of around 148-149°C and is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, particularly towards nucleophilic substitutions and electrophilic additions. Care should be taken to handle it under an inert atmosphere to avoid decomposition.

5-Bromo-1-isoindolinone (CAS: 552330-86-6) is commonly synthesized via the bromination of 1-isoindolinone using bromine in the presence of a suitable solvent such as dichloromethane. The reaction is performed under an inert atmosphere to prevent side reactions, and the yield is typically around 70-80%. The product is isolated by recrystallization from the appropriate solvent.

5-Bromo-1-isoindolinone (CAS: 552330-86-6) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of various pharmaceutical compounds, particularly in the development of new drugs. Additionally, it is utilized in the production of certain dyes and as an intermediate in the preparation of other organic compounds.

When handling 5-Bromo-1-isoindolinone (CAS: 552330-86-6), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or under a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. Safety data sheets (SDS) should be consulted for specific handling and disposal instructions.