4-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine(CAS: 1190310-00-9)

4-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine is a crystalline solid with a molecular weight of approximately 265.03 g/mol. It has limited water solubility and is soluble in common organic solvents like DMSO and DMF. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents.

4-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine is typically synthesized through bromination and methylation reactions. The process often involves the use of bromine and methyl iodide in the presence of a suitable base. The reaction is carried out in an inert solvent such as toluene, and the yield can be improved by careful control of reaction conditions and purification methods.

4-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine is utilized in various industries, particularly in pharmaceuticals for its potential as a drug intermediate. It is also explored in the sensor and semiconductor industries for its unique electronic and chemical properties.

When handling 4-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to prevent inhalation of vapors. Spills should be handled by carefully containing and disposing of them according to safety data sheet (SDS) guidelines. Proper training and adherence to safety protocols are essential to ensure safe laboratory practices.