(4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanone phosphate (1:1)(CAS: 1270138-41-4)

The compound (4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanone phosphate (1:1) has a molecular weight of approximately 625.5 g/mol. It is a white crystalline solid with a high solubility in water and poor solubility in organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution and addition reactions. It crystallizes in the monoclinic system.

The compound is typically synthesized through a multi-step process involving the condensation of 4-benzyl-1-piperazine carboxylic acid, 2-(3-methylbutylamino)-3-pyridinecarboxaldehyde, and methanone, followed by the addition of a phosphate group. Commonly used catalysts include triphenylphosphine and triethylamine to enhance reactivity and yield, with a typical yield of 70-80%.

This compound is primarily used in the pharmaceutical industry for its potential as a drug intermediate. It may also have applications in the field of chromatography as a stationary phase for certain analytical methods. Additionally, it could be used in the development of new materials and sensors due to its unique chemical structure.

When handling (4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanone phosphate (1:1), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Handle the compound in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, neutralize it with an appropriate chemical neutralizer and dispose of it according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines.